王大毛,辽宁铁岭人,教授,硕士生导师
教育经历
2003.9-2007.7 西北农林科技大学, 食品科学与工程, 本科
2007.9-2010.6 西北农林科技大学, 粮食油脂及植物蛋白质工程, 硕士
2012.3-2016.8 高丽大学(韩国), 食品生物技术, 博士
工作经历
2010.7-2011.2 上海润盈生物工程有限公司, 研发经理
2016.8-2018.8 瑞典皇家理工学院,化学,生物技术与健康学院,博士后
2018.9-2019.8 瑞典皇家理工学院,化学,生物技术与健康学院,特聘研究员
2017.6-2017.10 斯德哥尔摩大学,材料学院, 访问学者(兼)
学术情况概述
研究方向主要包括碳水化合物酶工程,代谢工程,生物质精炼技术等。获国家发明专利一项,韩国,美国发明专利共3项。主持国家自然科学基金面上项目,重庆市自然科学基金面上项目,瑞典瓦伦堡木材科学中心项目等多项。担任frontiers in chemistry客座编辑,food chemistry,journal of agricultural and food chemistry,carbohydrate polymers,biotechnology for biofuels, journal of biotechnology, journal of chromatography b, process biochemistry,plos one, bioresource technology等期刊的审稿人。
发表论文
yuting zheng, yanping li, yuanyuan yang, ye zhang, di wang, peiyao wang, ann c. y. wong, yves s. y. hsieh, and damao wang. recent advances in bioutilization of marine macroalgae carbohydrates: degradation, metabolism, and fermentation. journal of agricultural and food chemistry 2022 70 (5), 1438-1453
peiyao wang, yuting zheng, yanping li, ji shen, meiling dan, damao wang, recent advances in biotransformation, extraction and green production of d-mannose, current research in food science, volume 5, 2022,
li, yanping, yuting zheng, ye zhang, yuanyuan yang, peiyao wang, balázs imre, ann c.y. wong, yves s.y. hsieh, and damao wang. 2021. "brown algae carbohydrates: structures, pharmaceutical properties, and research challenges" marine drugs 19, no. 11: 620.
he y, ye f, li s, wang d, chen j, zhao g. effect of sand-frying-triggered puffing on the multi-scale structure and physicochemical properties of cassava starch in dry gel. biomolecules. 2021 dec 14;11(12):1872.
jing li, damao wang, shu-chieh chang, pi-hui liang, vaibhav srivastava, shih-yun guu, jiun-jie shie, kay-hooi khoo, vincent bulone, and yves s. y. hsieh. production of structurally defined chito-oligosaccharides with a single n-acetylation at their reducing end using a newly discovered chitinase from paenibacillus pabuli. journal of agricultural and food chemistry 2021 69 (11), 3371-3379
wang d, li y, zheng y, hsieh ysy. recent advances in screening methods for the functional investigation of lytic polysaccharide monooxygenases. front chem. 2021;9:653754. published 2021 apr 12.
yulin wang, jia chen, damao wang, fayin ye, yonglin he, zicong hu, guohua zhao, a systematic review on the composition, storage, processing of bamboo shoots: focusing the nutritional and functional benefits, journal of functional foods,volume 71, 2020, 104015,
j li, d wang, x xing, tjr cheng, ph liang, v bulone, jh park. ysy hsieh. structural analysis and biological activity of cell wall polysaccharides extracted from panax ginseng marc. international journal of biological macromolecules . 2019. 135, 29-37
wang, d.; li, j.; salazar-alvarez, g.; mckee, l. s.; srivastava, v.; sellberg, j. a.; bulone, v.; hsieh, y. s. y., production of functionalised chitins assisted by fungal lytic polysaccharide monooxygenase. green chem 2018, 20 (9), 2091-2100.
wang, d. m.; li, j.; wong, a. c. y.; aachmann, f. l.; hsieh, y. s. y., a colorimetric assay to rapidly determine the activities of lytic polysaccharide monooxygenases. biotechnol biofuels 2018, 11.
wang, d. m.; aarstad, o. a.; li, j.; mckee, l. s.; saetrom, g. i.; vyas, a.; srivastava, v.; aachmann, f. l.; bulone, v.; hsieh, y. s. y., preparation of 4-deoxy-l-erythro-5-hexoseulose uronic acid (deh) and guluronic acid rich alginate using a unique exo-alginate lyase from thalassotalea crassostreae. j agr food chem 2018, 66 (6), 1435-1443.
wang, d.; kim, d. h.; yun, e. j.; park, y. c.; seo, j. h.; kim, k. h., the first bacterial beta-1,6-endoglucanase from saccharophagus degradans 2-40(t) for the hydrolysis of pustulan and laminarin. appl microbiol biot 2017, 101 (1), 197-204.
wang, d.; kim, d. h.; yoon, j. j.; kim, k. h., production of high-value beta-1,3-glucooligosaccharides by microwave-assisted hydrothermal hydrolysis of curdlan. process biochem 2017, 52, 233-237.
wang, d.; kim, d. h.; kim, k. h., effective production of fermentable sugars from brown macroalgae biomass. appl microbiol biot 2016, 100 (22), 9439-9450.
wang, d.; kim, d. h.; seo, n.; yun, e. j.; an, h. j.; kim, j. h.; kim, k. h., a novel glycoside hydrolase family 5 beta-1,3-1,6-endoglucanase from saccharophagus degradans 2-40(t) and its transglycosylase activity. appl environ microb 2016, 82 (14), 4340-4349.
wang, d.; yun, e. j.; kim, s.; kim, d. h.; seo, n.; an, h. j.; kim, j. h.; cheong, n. y.; kim, k. h., efficacy of acidic pretreatment for the saccharification and fermentation of alginate from brown macroalgae. bioproc biosyst eng 2016, 39 (6), 959-966.
kim, d. h.; wang, d.; yun, e. j.; kim, s.; kim, s. r.; kim, k. h., validation of the metabolic pathway of the alginate-derived monomer in saccharophagus degradans 2-40(t) by gas chromatography-mass spectrometry. process biochem 2016, 51 (10), 1374-1379.
wang, d. m.; kim, h. t.; yun, e. j.; kim, d. h.; park, y. c.; woo, h. c.; kim, k. h., optimal production of 4-deoxy-l-erythro-5-hexoseulose uronic acid from alginate for brown macro algae saccharification by combining endo- and exo-type alginate lyases. bioproc biosyst eng 2014, 37 (10), 2105-2111.
kim, h. t.; yun, e. j.; wang, d.; chung, j. h.; choi, i. g.; kim, k. h., high temperature and low acid pretreatment and agarase treatment of agarose for the production of sugar and ethanol from red seaweed biomass. bioresource technol 2013, 136, 582-587.
kim, h. t.; chung, j. h.; wang, d.; lee, j.; woo, h. c.; choi, i. g.; kim, k. h., depolymerization of alginate into a monomeric sugar acid using alg17c, an exo-oligoalginate lyase cloned from saccharophagus degradans 2-40. appl microbiol biot 2012, 93 (5), 2233-2239.
授权专利
novel beta-1,3-1,6-endoglucanase for producing oligosacchairdes and glucose from beta-glucan, 韩国专利, 2017, 10-1804050
novel beta-1,6-endoglucanase for producing gentiobiose and glucose from beta-glucan, 韩国专利, 2017, 10-1784665
novel beta-1,3-1,6-endoglucanase producing, from beta-glucan, oligosaccharides or glucose. us 2020/0002738 a1, 美国专利
由beta-葡聚糖中产生龙胆二糖或葡萄糖的新型beta-1,6-内切葡聚糖酶. 中国专利,201780042236.3
科研项目
开发新型多糖单加氧酶用于木材细胞壁降解. 瑞典瓦伦堡木材科学中心项目,100万瑞典克朗,2016-2018,主持
海洋生物质的生物精炼技术开发. 欧盟era-net项目,218万欧元,2016-2019,参与
海洋多糖生物质的生物转化与功能化,西南大学引进人才启动项目,2020-2023,50万元,主持
新型海藻酸裂解酶催化机制及海藻寡糖工业酶催化剂开发,重庆市留学回国人员创新创业项目,2020-2021, 8万元,主持
红藻来源添加代糖3.6脱水l半乳糖的高效绿色制备,益生菌发酵纯化及健康评价研究,广西农产资源化学与生物技术重点实验室开放课题,2021-2023, 2.5万元,主持
高耐热褐藻多糖裂解酶结构与催化机制解析及定向进化, 重庆市自然科学基金面上项目, 2020-2023, 10万元,主持
组氨酸甲基化及氧化铁光催化对甲壳素多糖单加氧酶的催化机制研究,国家自然科学基金面上项目,2022-2025,59万元,主持
学术活动(部分)
2019亚洲生物技术研讨会(acb2019,台北),大会演讲
2018斯德哥尔摩细胞壁学会,大会演讲,学术评委
2017斯德哥尔摩细胞壁学会,大会演讲,学术评委
2016第十一届世界代谢工程学会(神户),大会报告
2016韩国代谢组学学会(首尔),大会演讲
2015第37 届世界生物技术与能源学会(圣迭戈) 大会报告
j9九游会老哥俱乐部交流区的联系方式
西南大学食品科学学院
重庆市北碚区天生路2号
邮政编码:400715
电话:17729655321
e-mail: wangdamao@swu.edu.cn
学术九游会登陆主页:https://www.researchgate.net/profile/damao_wang
欢迎对食品生物技术,酶工程,生物资源利用等领域感兴趣的同学加入实验室!